Role of γ-aminobutyric acidA (GABAA) receptors in drugs of abuse

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Differentiating the role of γ -aminobutyric acid type A (GABAA) receptor subtypes

The inhibitory tone maintained throughout the central nervous system relies predominantly on the activity of neuronal GABAA (γ -aminobutyric acid type A) receptors. This receptor family comprises various subtypes that have unique regional distributions, but little is known about the role played by each subtype. The majority of the receptors contain a γ 2 subunit and are sensitive to modulation ...

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ژورنال

عنوان ژورنال: Japanese Journal of Pharmacology

سال: 1995

ISSN: 0021-5198

DOI: 10.1016/s0021-5198(19)35553-2